Deadenylate is a term used in biological processes to describe the removal of the poly(A) tail from an mRNA molecule. Other synonyms for the term include deadenylation, deadenylating, or poly(A) tail shortening. These processes are crucial to regulate gene expression and control mRNA turnover. Without proper deadenylation, mRNA molecules would accumulate and induce negative outcomes for cellular functions. Different proteins and enzymes are involved in deadenylation, such as poly(A)-specific ribonuclease (PARN) or deadenylases. The understanding of these molecular mechanisms is critical to comprehend various biological processes, including embryonic development, inflammation, and immune responses.