The phrase "most numbskull" refers to someone who is extremely foolish or idiotic. Antonyms for this phrase could include "clever," "intelligent," "astute," "wise," and "sharp." These adjectives describe individuals who possess good judgment, are quick-witted, and can easily solve problems. Their mental abilities are keen, and they make wise decisions in a variety of situations. Antonyms for "most numbskull" can also include "smart," "bright," "sharp-witted," and "knowledgeable." These words highlight the fact that the opposite of foolishness is intelligence, and that someone with a sharp mind can avoid making the kinds of mistakes that a numbskull might make.